Helius Medical PoNS study on brain activity in peer-reviewed journal
Helius Medical Technologies (NASDAQ:HSDT; TSX:HSM) reported that a scientific paper entitled, “Human Translingual Neurostimulation Alters Resting Brain Activity in High-density EEG,” was published in the latest edition of the peer-reviewed Journal of NeuroEngineering and Rehabilitation.
The high-density array electroencephalograph (EEG) study of Helius’ Portable Neuromodulation Stimulator (PoNS) demonstrates brain activity changes following exposure to both high frequency pulse (HFP) and low frequency pulse (LFP) versions of the PoNS device used in the company’s traumatic brain injury clinical trials.
The Centre for Neurology Studies at HealthTech Connex in Surrey, British Columbia conducted the EEG study. The experiment involved 20 healthy individuals participating in a two-week, within-subject, crossover design that compared 20 minutes of PoNS stimulation between HFP and LFP devices. All participants received both HFP and LFP PoNS stimulation, with EEG measurements before, during and after stimulation. EEG measurements examined frequency and spatial activation changes directly resulting from PoNS stimulation.
“We know that the brain’s underlying neuromodulation response to stimulation is complex and elegant, and we are excited to see the next waves of results to enable us to further understand the effects of the PoNS device through an array of advanced neuroimaging techniques,” Dr. Ryan D’Arcy, principal author of the study, said in a statement.
The effects continued both immediately after stimulation and into the following week of the study, after just one 20-minute session,” he added.
An electronic copy of the paper can be accessed online here.