Stifel upgraded Tetraphase Pharmaceuticals (NASDAQ:TTPH) to “buy” from “hold” and raised its price target to $15 from $8 after the company reported positive top-line results of the IGNITE4 clinical trial evaluating its eravacycline in patients with complicated intra-abdominal infections (cIAI). The stock closed at $6.90 on July 25.Read More
Stifel upgraded Durect (NASDAQ:DRRX) to “buy” from “hold” and raised its price target to $3 from $1.25 and also transitioned coverage to Adam Walsh from Annabel Samimy. The stock closed at $1.59 on July 11.Read More
Stifel downgraded Argos Therapeutics (NASDAQ:ARGS) to “hold” from “buy” and slashed its price target to $1.40 from $10 after an independent data monitoring committee (IDMC) recommended discontinuation of the ADAPT Phase 3 trial of AGS-003 in metastatic renal cell carcinoma (RCC) patients.Read More
Maxim Group downgraded Pluristem Therapeutics (NASDAQ:PSTI) to “hold” from “buy” and eliminated its price target, saying it is not in agreement with the company in terms of its clinical plans. The stock closed at $1.14 on Feb. 13.Read More
Maxim Group downgraded Galena Biopharma (NASDAQ:GALE) to “hold” from “buy” and removed its price target after the departure of Galena CEO, Dr. Mark Schwartz. The stock was quoted at $1.11 at midday Feb. 2.Read More
Stifel downgraded Ocera Therapeutics (NASDAQ:OCRX) to “hold” from “buy” and slashed its price target to $1 from $9 after the company reported top-line results from a Phase 2b study evaluating ornithine phenylacetate (OCR-002) in hospitalized patients with hepatic encephalopathy (HE).Read More
Maxim Group upgraded ADMA Biologics (NASDAQ:ADMA) to ‘buy” from “hold” and established a price target of $13 after the company agreed to acquire Biotest Pharmaceuticals’ immunoglobulin manufacturing facility in Florida. The stock was quoted at $5.54 in afternoon trading on Jan. 24.Read More
Craig-Hallum downgraded Nobilis Health (NASDAQ:HLTH) to “hold” from “buy” and slashed its price target to $2 from $6. The stock closed at $2.25 on Dec. 12.Read More
Stifel downgraded Nivalis Therapeutics (NASDAQ:NVLS) to “ hold” from “buy” and slashed its price target to $3.25 from $16 after the company released Phase 2 data for cavosonstat in the treatment of patients with homozygous F508del CF that were stably on Orkambi. The stock closed at $6.25 on Monday.Read More
Maxim Group upgraded Keryx Biopharmaceuticals (NASDAQ:KERX) to “buy” from “hold” and reinstated its $7 price target after the FDA approved its application for a second contract manufacturer of Auryxia for the control of serum phosphorus levels in patients with CKD on dialysis.
Shares of Keryx were changing hands at $5.35, up 56 cents, in afternoon trading on Wednesday.Read More
Stifel downgraded Tandem Diabetes (NASDAQ:TNDM) to “hold” from “buy” and slashed its price target to $3.50 from $15 after a more disappointing than expected third quarter earnings performance and now sharply lower implied fourth guidance. The stock closed at $5.35 on Tuesday.
“Multiple factors driving increased near-term uncertainty are making Tandem highly difficult to model,” writes analyst Rick Wise, “The most significant and most incremental headwind is the much larger than anticipated negative impact the MDT 630/670G product launch/approval is having on the market.”Read More
Maxim Group downgraded Opexa Therapeutics (NASDAQ:OPXA) to “hold” from “buy” and removed its previous price target of $18 after the company failed a Phase 2b trial in secondary progressive multiple sclerosis (SPMS). The stock is changing hands at $1.02, down $2.37, in trading Friday afternoon.
Opexa’s T cell-based immunotherapy, Tcelna, did not meet the primary endpoint of brain atrophy and the secondary endpoint of reduced rate of disease progression also was not metRead More
Canaccord Genuity has downgraded AngioDynamics (NASDAQ:ANGO) to “hold” from “buy” and reduced its price target to $13 from $14.50, following the abrupt departure of CEO, Joe DeVivo, “which we think will heighten investor concern near term, and increase uncertainty.” The stock closed at $12.14 on Monday.
“What’s more, this change compounds myriad existing challenges that have produced sluggish and inconsistent performance in the business over the past year,” writes analyst Jason Mills.Read More